Journal: Evidence-based Complementary and Alternative Medicine : eCAM

Article Title: Hirsutella sinensis Treatment Shows Protective Effects on Renal Injury and Metabolic Modulation in db/db Mice

doi: 10.1155/2019/4732858

Figure Lengend Snippet: Metabolic patterns of mice at 18 weeks based on multivariate statistical analysis of data from the GC-MS and HPLC-QTOF/MS showed that HS regulated the metabolic disorder of diabetic mice towards normal levels. Score plots of the four groups and their PCA models for plasma (a), urine (b), and kidney (c) data. The PLS-DA models for plasma (d), urine (e), and kidney (f) data. Db/db versus db/m groups and their OPLS-DA models for plasma (g), urine (h), and kidney (i) data. Db/db versus HS groups and their OPLS-DA models for plasma (j), urine (k), and kidney (l) data. The blank dots represent the QC group. The green dots represent the db/m group. The red dots represent the db/db group. The blue dots represent the HS treatment group. The brown dots represent the positive treatment group.

Article Snippet: The mass scan ranged between m/z 50–700, and the detector voltage was set at −1050 V. The metabolite identification was performed with the GC-MS Labsolutions software (Version 2.61, Shimadzu Corp., Tokyo, Japan) and databases such as Wiley 9 (Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany), National Institute of Standards and Technology (NIST) library 2.0 (2012) and the in-house mass spectra library database established in our laboratory.

Techniques: Gas Chromatography-Mass Spectrometry